An effective way to increase copy number using pre-enrichment prior to PCR amplification
A New Approach to Overcome Low Detection Limits. Over millions of years, tick-borne pathogens have adapted to the host in a way that ensures their survival. They evolved and developed strategies to evade and down-regulate the immune response and hide in tissues to avoid being attacked by immune cells, antibodies, complement, and other immune reactive elements. The evolution of those stealth pathogens introduced many challenges to laboratories trying to diagnose infections with tick-borne pathoge...